Introduction: In December 2019, a new RNA-beta coronavirus infection emerged in Wuhan, China. Sadikova 1 1Center of Endokrinology, Tashkent, Uzbekistan P002 Role COVID-19 infection on the development of type 1 diabetes in children and teenagers M. Hypoglycemia and nocturnal hypoglycemia were positively correlated to CV (p = 0.002 and p = 0.01, respectively) and negatively correlated to TIR (p = 0.039 and p = 0.009, respectively).Ĭonclusions: Children with T1DM on insulin pump showed glycemic improvement with decreased acute complications during the COVID-19 pandemic. A significant increase in the daily insulin dose (p = 0.001), basal % (p = 0.011), TIR (p = 0.009), CV (p = 0.001) and HbA1C (p = 0.001) occurred during the COVID-19 pandemic with a significant decrease in the frequency of DKA (p = 0.001) and hypoglycemia (p = 0.004). Their median time in range (TIR) was 57%, and their mean coefficient of variation (CV) was 38.2%. The mean insulin requirement of the studied children with T1DM during the COVID-19 pandemic was 0.88 ± 0.30 U/kg/day. Results: A 29 children (69%) had insulin-pump problems in the form of skin irritation (31%), skin infection (7.1%) and pump obstruction (31%). Data were compared to those obtained from the patients' medical records 1 year previously. Continuous-glucose monitoring was done using Medtronic i-pro device for 5 days. Methods: A 42 children with T1DM on insulin pump for at least 1 year were assessed for insulin requirements, insulin-pump problems, frequency of diabetic-ketoacidosis (DKA), hypoglycemia, and HbA1C. Objectives: To assess the impact of COVID-19 on glycemic control and acute complications among children with T1DM on insulin pump in Egypt. However, some studies reported glycemic improvement in these children during the pandemic. Children with type 1 diabetes (T1DM) are at risk of glycemic deterioration during the COVID-19 pandemic. Introduction: COVID-19 has impacted the lives of individuals worldwide especially those with chronic illnesses. Ayoup 2 1Ain Shams University, Cairo, Egypt, 2Al Rahmaneya Hospital, El Behera, Egypt POSTER TOUR 1-COVID # 1 P001 Glycemic variability and time in range among children with type 1 diabetes on insulin pump during the COVID-19 pandemic A.
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